For laboratory research use only. Not for human consumption. All compounds referenced in this article are sold by Explicit SARMs solely as reference materials for in-vitro and animal research by qualified professionals. Nothing here is medical advice, and no statement has been evaluated by the FDA. These materials are not intended to diagnose, treat, cure or prevent any disease.
Most “TB-500 reviews” online are product testimonials. This one reviews the research: what TB-500 is, what has been studied, and where the gaps are.
What Is TB-500?
TB-500 is a synthetic peptide based on the actin-binding region of thymosin beta-4, a naturally occurring 43-amino-acid protein that regulates actin, the main structural protein of the cell cytoskeleton. TB-500 is the fragment, and thymosin beta-4 is the full-length protein. Keeping the two apart is the single most important point when reading the literature.
What Has Been Studied
Thymosin beta-4 is one of the main proteins cells use to sequester actin monomers. Preclinical research has examined it in cell-migration, wound-healing and blood-vessel-formation models. Much less work has been done on TB-500 specifically, and many claims about the fragment actually cite studies of the full protein.
Evidence Gaps
- Most findings come from cell and animal models.
- Results for full-length thymosin beta-4 can’t be assumed to apply to TB-500.
- Published data on TB-500 combined with other peptides, such as BPC-157, are sparse.
Our TB-500 research summary looks at these points in more depth.
Regulatory Status
TB-500 is not approved by the FDA or any other regulator for any indication. TB-500 and thymosin beta-4 appear on the World Anti-Doping Agency’s prohibited list under S2 (peptide hormones, growth factors, related substances and mimetics).
Research Material
Explicit SARMs supplies TB-500 5mg, TB-500 10mg and TB-500 Capsules strictly as laboratory reference material. A certificate of analysis is available on request through our contact page, and our products are tested by Accumark. Our guide to reading a COA explains what each section of the report should contain.
Frequently Asked Questions
Is TB-500 the same as thymosin beta-4?
No. TB-500 is a synthetic fragment based on part of thymosin beta-4.
Is TB-500 for human use?
No. It is sold strictly for laboratory research, and we do not provide dosing, administration or usage guidance.