LGD-4033 Ligandrol Capsules

For laboratory research use only. Not for human consumption. Sold by Explicit SARMs solely as reference material for in-vitro and animal research by qualified professionals. Not evaluated by the FDA and not intended to diagnose, treat, cure or prevent any disease.

LGD-4033 is CAS 1165910-22-4, formula C14H12F6N2O, molecular weight 338.3. Ligand Pharmaceuticals discovered it, and Viking Therapeutics later licensed it as VK5211. Structurally it’s a pyrrolidinyl-benzonitrile, a different scaffold from the aryl-propionamide SARMs like ostarine, which matters if you’re comparing receptor data across the class.

What has been published

The anchor paper is Basaria et al. (J Gerontol A Biol Sci Med Sci 2013, PMID 22459616), a 21-day placebo-controlled phase 1 study in 76 healthy young men. It reported a long elimination half-life, dose-dependent suppression of total testosterone, SHBG and HDL cholesterol, and an increase in lean body mass by DXA. The HDL finding is the one most often carried into later protocols as a secondary endpoint.

Viking then ran a phase 2 trial in patients recovering from hip fracture (NCT02578095). In rodents, Roch et al. (2020, PMID 33042018) compared ligandrol with ostarine in ovariectomized rats.

There’s a safety thread too. Barbara et al. (2020, PMID 33062783) described drug-induced liver injury associated with unregulated supplements labeled as containing LGD-4033 and RAD-140. Composition of those products wasn’t verified, but lipid and liver panels make sense in study design.

For the full review, see LGD-4033 (Ligandrol) Research.

RAD-140, the other compound named in that case report, is available as RAD-140 (testolone) capsules in the same 90 x 10mg format.

Related research capsules in the same 90 x 10mg format include Ostarine MK-2866, Cardarine GW-501516, and MK-777 (acetamoren).

Specifications

• Compound: LGD-4033 (ligandrol, VK5211)
• CAS: 1165910-22-4
• Formula / MW: C14H12F6N2O / 338.3
• Class: nonsteroidal SARM
• Format: 90 capsules, 10mg per capsule
• WADA: named in S1.2, prohibited at all times

Testing and COA

LGD-4033 comes to us from US domestic manufacturing partners. Our manufacturer tests it twice during production, and we use an independent third-party lab for purity testing. Ask for a COA through our contact page.

FAQ

Is LGD-4033 the same as VK5211?

Yes. VK5211 is Viking Therapeutics’ development code for the same compound.

How much do LGD-4033 Ligandrol Capsules cost, and where can I buy it?

As of November 2026, LGD-4033 Ligandrol Capsules from Explicit SARMs cost $80 for one bottle of 90 capsules at 10mg per capsule, and you can order directly on this page. US orders of $100 or more ship free, and orders placed before 2 PM ET, Monday to Friday, ship the same day. Sold for laboratory research use only.

Has LGD-4033 been tested in humans?

Yes, in a phase 1 study (Basaria 2013) and a phase 2 trial in hip-fracture patients. It is not approved for any use.

What did the phase 1 study report?

A long half-life, suppression of testosterone, SHBG and HDL, and increased lean body mass over 21 days.

Is it on the WADA list?

Yes, by name, in section S1.2.

Can it be used outside a lab?

No. It is sold for laboratory research only and is not for human consumption.

Who tests LGD-4033?

Our manufacturer tests LGD-4033 twice during production, and we use an independent third-party lab for purity testing.

What payment methods does Explicit SARMs accept?

We accept debit and credit cards, Zelle, Cash App, and ACH bank transfer.

Does Explicit SARMs ship internationally?

Yes. We ship within the United States, to Canada, and to other countries where local regulations allow the product. Available destinations and shipping options are shown at checkout.

For laboratory research use only. Not for human consumption. Sold by Explicit SARMs solely as reference material for in-vitro and animal research by qualified professionals. Not evaluated by the FDA and not intended to diagnose, treat, cure or prevent any disease.