Ostarine (MK-2866) vs RAD-140: Research Comparison

For laboratory research use only. Not for human consumption. Sold by Explicit SARMs solely as reference material for in-vitro and animal research by qualified professionals. Not evaluated by the FDA and not intended to diagnose, treat, cure or prevent any disease.

By Explicit SARMs Team

Ostarine (MK-2866, enobosarm) and RAD-140 (testolone) are both nonsteroidal selective androgen receptor modulators. Ostarine is one of the most extensively published SARMs, while RAD-140 is a later compound characterized mainly in preclinical work. This page compares them for laboratory research only.

Side-by-side comparison

Ostarine (MK-2866) RAD-140 (testolone)
Class Nonsteroidal SARM (aryl-propionamide) Nonsteroidal SARM
CAS 841205-47-8 1182367-47-0
Formula / MW C19H14F3N3O3 / 389.3 C20H16ClN5O2 / 393.8
Developer GTx, Inc. Radius Health
Key published paper Phase II study, Dalton et al. 2011 (PMID 22031847) Preclinical characterization, Miller et al. 2011 (PMID 24900290)
WADA Named in section S1 Named in section S1
Explicit SARMs formats 90 capsules, 10mg each; liquid 90 capsules, 10mg each; liquid, 30ml at 30mg/ml

What the literature covers

Ostarine (enobosarm) has the larger published record, including clinical-stage research by GTx (Dalton et al. 2011) and many analytical and review papers (Narayanan et al. 2018). RAD-140’s design paper describes its preclinical tissue-selectivity profile (Miller et al. 2011).

Structural differences

Ostarine belongs to the aryl-propionamide SARM family developed by GTx, while RAD-140 comes from a separate benzonitrile/oxadiazole series. Their different structures give them distinct analytical signatures, which matters when choosing reference material.

How Explicit SARMs tests these compounds

Our manufacturer tests it twice during production, and we use an independent third-party lab for purity testing. A COA is available on request.

Related research compounds

FAQ

Is Ostarine the same as MK-2866 and enobosarm?

Yes. Ostarine, MK-2866, enobosarm and GTx-024 are names for the same compound, CAS 841205-47-8.

What is the main difference between Ostarine and RAD-140?

Both are nonsteroidal androgen receptor ligands, but they come from different chemical series and developers. Ostarine has the larger published record, while RAD-140 is mainly characterized preclinically.

What formats does Explicit SARMs supply?

Both are available as 90-capsule bottles at 10mg per capsule and as liquids, for laboratory research use only.

How are they tested?

Our manufacturer tests it twice during production, and we use an independent third-party lab for purity testing. A COA is available on request.

Published research cited

  1. Dalton JT, et al. The selective androgen receptor modulator GTx-024 (enobosarm). J Cachexia Sarcopenia Muscle. 2011;2(3):153-161. PMID 22031847.
  2. Miller CP, et al. Design, synthesis, and preclinical characterization of the selective androgen receptor modulator (SARM) RAD140. ACS Med Chem Lett. 2011;2(2):124-129. PMID 24900290.
  3. Narayanan R, Coss CC, Dalton JT. Development of selective androgen receptor modulators (SARMs). Mol Cell Endocrinol. 2018;465:134-142. PMID 28624515.

Shopping Cart
Scroll to Top